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Department微细加工光学技术国家重点实验室(开放室)
Surface imaging microscopy with tunable penetration depth as short as 20 nm by employing hyperbolic metamaterials
Kong, Weijie1; Du, Wenjuan1,2; Liu, Kaipeng1; Liu, Hongchao1; Zhao, Zeyu1; Pu, Mingbo1; Wang, Changtao1; Luo, Xiangang1
Source PublicationJOURNAL OF MATERIALS CHEMISTRY C
Volume6Issue:7Pages:1797-1805
2018-02-21
Language英语
ISSN2050-7526
DOI10.1039/c7tc04748g
Indexed BySCI ; Ei
WOS IDWOS:000425309300022
EI Accession Number20180804822266
SubtypeJ
AbstractAdvancement in the understanding of biomolecular interactions has benefited from the development of surface imaging microscopy with high sensitivity and contrast. In this work, surface imaging microscopy with tunable penetration depth as short as 20 nm is proposed. By employing a hyperbolic metamaterial (HMM) composed of metal/dielectric multifilms, the deep subwavelength bulk plasmon polaritons (BPPs) are excited as the uniform and large area surface illumination source. Moreover, the penetration depth of the surface illumination structure could be continually tuned by changing the incidence angle of excitation light. In the experiments, a penetration depth of 25-38 nm in air is achieved at 532 nm by the HMM with Ag/SiO2 multilayers. Subsequently, a fluorescence pattern was imaged against another fluorescent background by this surface imaging microscopy, and the results indicate that distinct surface images with high contrast could indeed be obtained under BPP illumination with ultra-short penetration depth. This approach provides a promising avenue for tracking single-molecule and cell plasma membrane events.
KeywordCell membranes Fluorescence
WOS KeywordREFLECTION FLUORESCENCE MICROSCOPY ; SINGLE-MOLECULE DETECTION ; EPI-ILLUMINATION ; PLASMON MICROSCOPY ; FIELD ; CELLS ; EXCITATION ; SCATTERING ; GAIN ; TOOL
EI KeywordsCell membranes ; Fluorescence
EI Classification Number461.2 Biological Materials and Tissue Engineering ; 741.1 Light/Optics ; 951 Materials Science
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Document Type期刊论文
Identifierhttp://ir.ioe.ac.cn/handle/181551/9295
Collection微细加工光学技术国家重点实验室(开放室)
Affiliation1.State Key Laboratory of Optical Technologies on Nano-Fabrication and Micro-Engineering, Institute of Optics and Electronics, Chinese Academy of Science, P.O. Box 350, Chengdu; 610209, China;
2.University of Chinese Academy of Sciences, Beijing; 100049, China
Recommended Citation
GB/T 7714
Kong, Weijie,Du, Wenjuan,Liu, Kaipeng,et al. Surface imaging microscopy with tunable penetration depth as short as 20 nm by employing hyperbolic metamaterials[J]. JOURNAL OF MATERIALS CHEMISTRY C,2018,6(7):1797-1805.
APA Kong, Weijie.,Du, Wenjuan.,Liu, Kaipeng.,Liu, Hongchao.,Zhao, Zeyu.,...&Luo, Xiangang.(2018).Surface imaging microscopy with tunable penetration depth as short as 20 nm by employing hyperbolic metamaterials.JOURNAL OF MATERIALS CHEMISTRY C,6(7),1797-1805.
MLA Kong, Weijie,et al."Surface imaging microscopy with tunable penetration depth as short as 20 nm by employing hyperbolic metamaterials".JOURNAL OF MATERIALS CHEMISTRY C 6.7(2018):1797-1805.
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