Department | 微细加工光学技术国家重点实验室(开放室) |
Surface imaging microscopy with tunable penetration depth as short as 20 nm by employing hyperbolic metamaterials | |
Kong, Weijie1; Du, Wenjuan1,2; Liu, Kaipeng1; Liu, Hongchao1; Zhao, Zeyu1; Pu, Mingbo1; Wang, Changtao1; Luo, Xiangang1 | |
Source Publication | JOURNAL OF MATERIALS CHEMISTRY C
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Volume | 6Issue:7Pages:1797-1805 |
2018-02-21 | |
Language | 英语 |
ISSN | 2050-7526 |
DOI | 10.1039/c7tc04748g |
Indexed By | SCI ; Ei |
WOS ID | WOS:000425309300022 |
EI Accession Number | 20180804822266 |
Subtype | J |
Abstract | Advancement in the understanding of biomolecular interactions has benefited from the development of surface imaging microscopy with high sensitivity and contrast. In this work, surface imaging microscopy with tunable penetration depth as short as 20 nm is proposed. By employing a hyperbolic metamaterial (HMM) composed of metal/dielectric multifilms, the deep subwavelength bulk plasmon polaritons (BPPs) are excited as the uniform and large area surface illumination source. Moreover, the penetration depth of the surface illumination structure could be continually tuned by changing the incidence angle of excitation light. In the experiments, a penetration depth of 25-38 nm in air is achieved at 532 nm by the HMM with Ag/SiO2 multilayers. Subsequently, a fluorescence pattern was imaged against another fluorescent background by this surface imaging microscopy, and the results indicate that distinct surface images with high contrast could indeed be obtained under BPP illumination with ultra-short penetration depth. This approach provides a promising avenue for tracking single-molecule and cell plasma membrane events. |
Keyword | Cell membranes Fluorescence |
WOS Keyword | REFLECTION FLUORESCENCE MICROSCOPY ; SINGLE-MOLECULE DETECTION ; EPI-ILLUMINATION ; PLASMON MICROSCOPY ; FIELD ; CELLS ; EXCITATION ; SCATTERING ; GAIN ; TOOL |
EI Keywords | Cell membranes ; Fluorescence |
EI Classification Number | 461.2 Biological Materials and Tissue Engineering ; 741.1 Light/Optics ; 951 Materials Science |
Citation statistics | |
Document Type | 期刊论文 |
Identifier | http://ir.ioe.ac.cn/handle/181551/9295 |
Collection | 微细加工光学技术国家重点实验室(开放室) |
Affiliation | 1.State Key Laboratory of Optical Technologies on Nano-Fabrication and Micro-Engineering, Institute of Optics and Electronics, Chinese Academy of Science, P.O. Box 350, Chengdu; 610209, China; 2.University of Chinese Academy of Sciences, Beijing; 100049, China |
Recommended Citation GB/T 7714 | Kong, Weijie,Du, Wenjuan,Liu, Kaipeng,et al. Surface imaging microscopy with tunable penetration depth as short as 20 nm by employing hyperbolic metamaterials[J]. JOURNAL OF MATERIALS CHEMISTRY C,2018,6(7):1797-1805. |
APA | Kong, Weijie.,Du, Wenjuan.,Liu, Kaipeng.,Liu, Hongchao.,Zhao, Zeyu.,...&Luo, Xiangang.(2018).Surface imaging microscopy with tunable penetration depth as short as 20 nm by employing hyperbolic metamaterials.JOURNAL OF MATERIALS CHEMISTRY C,6(7),1797-1805. |
MLA | Kong, Weijie,et al."Surface imaging microscopy with tunable penetration depth as short as 20 nm by employing hyperbolic metamaterials".JOURNAL OF MATERIALS CHEMISTRY C 6.7(2018):1797-1805. |
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2018-2062.pdf(1832KB) | 期刊论文 | 出版稿 | 开放获取 | CC BY-NC-SA | View Application Full Text |
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