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Quantifying intraocular scatter with near diffraction-limited double-pass point spread function
Zhao, Junlei1,2,3; Xiao, Fei1,2; Kang, Jian1,2,3; Zhao, Haoxin1,2; Dai, Yun1,2; Zhang, Yudong1,2
2016
Source PublicationBiomedical Optics Express
ISSN2156-7086
Volume7Issue:11Pages:4595-4604
SubtypeJ
AbstractMeasurement of the double-pass (DP) point-spread function (PSF) can provide an objective and non-invasive method for estimating intraocular scatter in the human eye. The objective scatter index (OSI), which is calculated from the DP PSF images, is commonly used to quantify intraocular scatter. In this article, we simulated the effect of higher-order ocular aberrations on OSI, and the results showed that higher-order ocular aberrations had a significant influence on OSI. Then we developed an adaptive optics DP PSF measurement system (AO-DPPMS) which was capable of correcting ocular aberrations up to eighth-order radial Zernike modes over a 6.0-mm pupil. Employing this system, we obtained DP PSF images of four subjects at the fovea. OSI values with aberrations corrected up to 2nd, 5th and 8th Zernike order were calculated respectively, from the DP PSF images of the four subjects. The experimental results were consistent with the simulation, suggesting that it is necessary to compensate for the higher-order ocular aberrations for accurate intraocular scatter estimation. © 2016 Optical Society of America.
KeywordAdaptive Optics Imaging Systems Noninvasive Medical Procedures
DOI10.1364/BOE.7.004595
Indexed BySCI ; Ei
Language英语
Funding OrganizationNational Natural Science Foundation of China [61378064] ; National High Technology Research and Development Program of China [2015AA020511]
WOS IDWOS:000387557600020
Citation statistics
Document Type期刊论文
Identifierhttp://ir.ioe.ac.cn/handle/181551/8423
Collection自适应光学技术研究室(八室)
Affiliation1. The Key Laboratory on Adaptive Optics, Chinese Academy of Sciences, Chengdu
2.610209, China
3. The Laboratory on Adaptive Optics, Institute of Optics and Electronics, Chinese Academy of Sciences, Chengdu
4.610209, China
5. University of Chinese Academy of Sciences, Beijing
6.100049, China
Recommended Citation
GB/T 7714
Zhao, Junlei,Xiao, Fei,Kang, Jian,et al. Quantifying intraocular scatter with near diffraction-limited double-pass point spread function[J]. Biomedical Optics Express,2016,7(11):4595-4604.
APA Zhao, Junlei,Xiao, Fei,Kang, Jian,Zhao, Haoxin,Dai, Yun,&Zhang, Yudong.(2016).Quantifying intraocular scatter with near diffraction-limited double-pass point spread function.Biomedical Optics Express,7(11),4595-4604.
MLA Zhao, Junlei,et al."Quantifying intraocular scatter with near diffraction-limited double-pass point spread function".Biomedical Optics Express 7.11(2016):4595-4604.
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