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Morphological changes in Schlemm's canal in treated and newly diagnosed untreated glaucomatous eyes
Shi GuoHua; Fu LingLing; Li XiQi; Jiang ChunHui; Zhang YuDong; Zhang, YD (reprint author), Chinese Acad Sci, Inst Opt & Elect, Key Lab Adapt Opt, Chengdu 610209, Peoples R China.
Source PublicationSCIENCE CHINA-LIFE SCIENCES
Volume57Issue:12Pages:1213-1217
2014
Language英语
ISSN1674-7305
DOI10.1007/s11427-014-4732-0
Indexed BySCI
WOS IDWOS:000346187000009
Subtype期刊论文
AbstractA custom built 1310 nm center wavelength swept source optical coherence tomography instrument was used to measure morphological changes in treated and newly diagnosed untreated glaucomatous human Schlemm's canal (SC). Thirty-seven primary open-angle glaucoma patients were divided into two groups depending on the patients having been treated or not. The statistical results showed that there were significant differences between the treated and untreated groups' SC areas (treated, 7935.6875 +/- 680.003 mu m(2); untreated, 3890.71875 +/- 871.49844 mu m(2); P < 0.001), the circumferences (treated, 580.37891 +/- 44.96529 mu m; untreated, 381.9026 +/- 41.22123 mu m; P < 0.001), and the long diameters (treated, 272.87806 +/- 25.7254 mu m; untreated, 185.24047 +/- 19.72786 mu m; P < 0.001). We hypothesize that, after drug treatment, the SC will expand and the morphometric values especially the areas will become larger, thus helping to reduce intraocular pressure.; A custom built 1310 nm center wavelength swept source optical coherence tomography instrument was used to measure morphological changes in treated and newly diagnosed untreated glaucomatous human Schlemm's canal (SC). Thirty-seven primary open-angle glaucoma patients were divided into two groups depending on the patients having been treated or not. The statistical results showed that there were significant differences between the treated and untreated groups' SC areas (treated, 7935.6875 +/- 680.003 mu m(2); untreated, 3890.71875 +/- 871.49844 mu m(2); P < 0.001), the circumferences (treated, 580.37891 +/- 44.96529 mu m; untreated, 381.9026 +/- 41.22123 mu m; P < 0.001), and the long diameters (treated, 272.87806 +/- 25.7254 mu m; untreated, 185.24047 +/- 19.72786 mu m; P < 0.001). We hypothesize that, after drug treatment, the SC will expand and the morphometric values especially the areas will become larger, thus helping to reduce intraocular pressure.
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Cited Times:2[WOS]   [WOS Record]     [Related Records in WOS]
Document Type期刊论文
Identifierhttp://ir.ioe.ac.cn/handle/181551/6370
Collection自适应光学技术研究室(八室)
Corresponding AuthorZhang, YD (reprint author), Chinese Acad Sci, Inst Opt & Elect, Key Lab Adapt Opt, Chengdu 610209, Peoples R China.
Affiliation1.[Shi GuoHua
2.Li XiQi
3.Zhang YuDong] Chinese Acad Sci, Inst Opt & Elect, Key Lab Adapt Opt, Chengdu 610209, Peoples R China
4.[Fu LingLing] Karamay Cent Hosp, Karamay 834000, Peoples R China
5.[Jiang ChunHui] Fudan Univ, Dept Ophthalmol & Vis Sci Eye & ENT, Shanghai 200031, Peoples R China
Recommended Citation
GB/T 7714
Shi GuoHua,Fu LingLing,Li XiQi,et al. Morphological changes in Schlemm's canal in treated and newly diagnosed untreated glaucomatous eyes[J]. SCIENCE CHINA-LIFE SCIENCES,2014,57(12):1213-1217.
APA Shi GuoHua,Fu LingLing,Li XiQi,Jiang ChunHui,Zhang YuDong,&Zhang, YD .(2014).Morphological changes in Schlemm's canal in treated and newly diagnosed untreated glaucomatous eyes.SCIENCE CHINA-LIFE SCIENCES,57(12),1213-1217.
MLA Shi GuoHua,et al."Morphological changes in Schlemm's canal in treated and newly diagnosed untreated glaucomatous eyes".SCIENCE CHINA-LIFE SCIENCES 57.12(2014):1213-1217.
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