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Comparison of Schlemm's canal's biological parameters in primary open-angle glaucoma and normal human eyes with swept source optical
Wang, Fei3; Shi, Guohua1,2; Li, Xiqi1,2; Lu, Jing1,2; Ding, Zhihua4; Sun, Xinghuai3; Jiang, Chunhui3; Zhang, Yudong1,2; Shi, G. (guohua_shi@yahoo.com.cn)
Source PublicationJournal of Biomedical Optics
Volume17Issue:11Pages:116008
2012
Language英语
ISSN10833668
DOI10.1117/1.JBO.17.11.116008
Indexed ByEi
WOS IDWOS:000314502700022
Subtype期刊论文
AbstractThirty-seven normal and primary open angle glaucoma (POAG) subjects were noninvasively imaged by a tailor-made real-time anterior segment swept source optical coherence tomography (SS-OCT) to demonstrate the differences of the Schlemm's canal (SC) between POAG and normal eyes. After the cross-section images of the anterior chamber angle were acquired by SS-OCT, SC was confirmed by two independent masked observers and the average area, long diameter, and perimeter of the SC were measured. In normal subjects the circumference, area, and long diameter is 580.34 ± 87.81 μm, 8023.89 ± 1486.10 μm2, and 272.83 ± 49.39 μm, respectively, and these parameters were 393.25 ± 98.04 μm, 3941.50 ± 1210.69 μm 2, and 190.91 ± 46.47 μm in the POAG subjects. The area of SC in the normal ones was significantly larger than that in POAG eyes (p < 0.001), so as the long diameter and the perimeter (p < 0.001; p < 0.001). © 2012 Society of Photo-Optical Instrumentation Engineers (SPIE).; Thirty-seven normal and primary open angle glaucoma (POAG) subjects were noninvasively imaged by a tailor-made real-time anterior segment swept source optical coherence tomography (SS-OCT) to demonstrate the differences of the Schlemm's canal (SC) between POAG and normal eyes. After the cross-section images of the anterior chamber angle were acquired by SS-OCT, SC was confirmed by two independent masked observers and the average area, long diameter, and perimeter of the SC were measured. In normal subjects the circumference, area, and long diameter is 580.34 ± 87.81 μm, 8023.89 ± 1486.10 μm2, and 272.83 ± 49.39 μm, respectively, and these parameters were 393.25 ± 98.04 μm, 3941.50 ± 1210.69 μm 2, and 190.91 ± 46.47 μm in the POAG subjects. The area of SC in the normal ones was significantly larger than that in POAG eyes (p < 0.001), so as the long diameter and the perimeter (p < 0.001; p < 0.001). © 2012 Society of Photo-Optical Instrumentation Engineers (SPIE).
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Cited Times:18[WOS]   [WOS Record]     [Related Records in WOS]
Document Type期刊论文
Identifierhttp://ir.ioe.ac.cn/handle/181551/6321
Collection自适应光学技术研究室(八室)
Corresponding AuthorShi, G. (guohua_shi@yahoo.com.cn)
Affiliation1. Chinese Academy of Sciences, Key Laboratory on Adaptive Optics, Chengdu 610209, China
2. Institute of Optics and Electronic, Chinese Academy of Sciences, Chengdu 610209, China
3. Department of Ophthalmology and Vision Science, Eye and ENT, Fudan University, Shanghai 200031, China
4. State Key Laboratory of Modern Optical Instrumentation, Zhejiang University, Hangzhou 310027, China
Recommended Citation
GB/T 7714
Wang, Fei,Shi, Guohua,Li, Xiqi,et al. Comparison of Schlemm's canal's biological parameters in primary open-angle glaucoma and normal human eyes with swept source optical[J]. Journal of Biomedical Optics,2012,17(11):116008.
APA Wang, Fei.,Shi, Guohua.,Li, Xiqi.,Lu, Jing.,Ding, Zhihua.,...&Shi, G. .(2012).Comparison of Schlemm's canal's biological parameters in primary open-angle glaucoma and normal human eyes with swept source optical.Journal of Biomedical Optics,17(11),116008.
MLA Wang, Fei,et al."Comparison of Schlemm's canal's biological parameters in primary open-angle glaucoma and normal human eyes with swept source optical".Journal of Biomedical Optics 17.11(2012):116008.
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