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题名:
Comparison of Schlemm's canal's biological parameters in primary open-angle glaucoma and normal human eyes with swept source optical
作者: Wang, Fei3; Shi, Guohua1,2; Li, Xiqi1,2; Lu, Jing1,2; Ding, Zhihua4; Sun, Xinghuai3; Jiang, Chunhui3; Zhang, Yudong1,2
刊名: Journal of Biomedical Optics
出版日期: 2012
卷号: 17, 期号:11, 页码:116008
学科分类: Hydraulic structures - Ophthalmology
DOI: 10.1117/1.JBO.17.11.116008
通讯作者: Shi, G. (guohua_shi@yahoo.com.cn)
文章类型: 期刊论文
中文摘要: Thirty-seven normal and primary open angle glaucoma (POAG) subjects were noninvasively imaged by a tailor-made real-time anterior segment swept source optical coherence tomography (SS-OCT) to demonstrate the differences of the Schlemm's canal (SC) between POAG and normal eyes. After the cross-section images of the anterior chamber angle were acquired by SS-OCT, SC was confirmed by two independent masked observers and the average area, long diameter, and perimeter of the SC were measured. In normal subjects the circumference, area, and long diameter is 580.34 ± 87.81 μm, 8023.89 ± 1486.10 μm2, and 272.83 ± 49.39 μm, respectively, and these parameters were 393.25 ± 98.04 μm, 3941.50 ± 1210.69 μm 2, and 190.91 ± 46.47 μm in the POAG subjects. The area of SC in the normal ones was significantly larger than that in POAG eyes (p < 0.001), so as the long diameter and the perimeter (p < 0.001; p < 0.001). © 2012 Society of Photo-Optical Instrumentation Engineers (SPIE).
英文摘要: Thirty-seven normal and primary open angle glaucoma (POAG) subjects were noninvasively imaged by a tailor-made real-time anterior segment swept source optical coherence tomography (SS-OCT) to demonstrate the differences of the Schlemm's canal (SC) between POAG and normal eyes. After the cross-section images of the anterior chamber angle were acquired by SS-OCT, SC was confirmed by two independent masked observers and the average area, long diameter, and perimeter of the SC were measured. In normal subjects the circumference, area, and long diameter is 580.34 ± 87.81 μm, 8023.89 ± 1486.10 μm2, and 272.83 ± 49.39 μm, respectively, and these parameters were 393.25 ± 98.04 μm, 3941.50 ± 1210.69 μm 2, and 190.91 ± 46.47 μm in the POAG subjects. The area of SC in the normal ones was significantly larger than that in POAG eyes (p < 0.001), so as the long diameter and the perimeter (p < 0.001; p < 0.001). © 2012 Society of Photo-Optical Instrumentation Engineers (SPIE).
收录类别: Ei
项目资助者: National Science Foundation of China [61108082] ; Knowledge Innovation Program of the Chinese Academy of Sciences [KGCX2-Y11-920] ; Research Foundation of Fudan University [JJF158005]
语种: 英语
WOS记录号: WOS:000314502700022
ISSN号: 10833668
Citation statistics:
内容类型: 期刊论文
URI标识: http://ir.ioe.ac.cn/handle/181551/6321
Appears in Collections:自适应光学技术研究室(八室)_期刊论文

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作者单位: 1. Chinese Academy of Sciences, Key Laboratory on Adaptive Optics, Chengdu 610209, China
2. Institute of Optics and Electronic, Chinese Academy of Sciences, Chengdu 610209, China
3. Department of Ophthalmology and Vision Science, Eye and ENT, Fudan University, Shanghai 200031, China
4. State Key Laboratory of Modern Optical Instrumentation, Zhejiang University, Hangzhou 310027, China

Recommended Citation:
Wang, Fei,Shi, Guohua,Li, Xiqi,et al. Comparison of Schlemm's canal's biological parameters in primary open-angle glaucoma and normal human eyes with swept source optical[J]. Journal of Biomedical Optics,2012,17(11):116008.
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