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Measurement of oxygen saturation in small retinal vessels with adaptive optics confocal scanning laser ophthalmoscope
Li Hao; Jinglu; guohuashiyudongzhang
Source PublicationJournal of Biomedical Optics Vol.16(11) november 2011;Pubilshed:nov.10 2011
Volume16Issue:11
2011
Language英语
Subtype期刊论文
AbstractWe have used an adaptive optics confocal scanning laser ophthalmoscope to assess oxygen saturation in small retinal vessels. Images of the vessels with a diameter smaller than 50 μm are recorded at oxygen sensitive and isosbestic wavelengths (680 and 796 nm, respectively). The vessel optical densities (ODs) are determined by a computer algorithm. Then, OD ratios (ODRs), which are inversely proportional to oxygen saturation, are calculated. The results show that arterial ODRs are significantly smaller than venous ODRs, indicating that oxygen saturation in the artery is higher than that in the vEin. To the best of our knowledge, this is the first noninvasive measurement of oxygen saturation in small retinal vessels.; We have used an adaptive optics confocal scanning laser ophthalmoscope to assess oxygen saturation in small retinal vessels. Images of the vessels with a diameter smaller than 50 μm are recorded at oxygen sensitive and isosbestic wavelengths (680 and 796 nm, respectively). The vessel optical densities (ODs) are determined by a computer algorithm. Then, OD ratios (ODRs), which are inversely proportional to oxygen saturation, are calculated. The results show that arterial ODRs are significantly smaller than venous ODRs, indicating that oxygen saturation in the artery is higher than that in the vEin. To the best of our knowledge, this is the first noninvasive measurement of oxygen saturation in small retinal vessels.
Document Type期刊论文
Identifierhttp://ir.ioe.ac.cn/handle/181551/6213
Collection自适应光学技术研究室(八室)
Corresponding AuthorLi Hao
Affiliation中国科学院光电技术研究所
Recommended Citation
GB/T 7714
Li Hao,Jinglu,guohuashiyudongzhang. Measurement of oxygen saturation in small retinal vessels with adaptive optics confocal scanning laser ophthalmoscope[J]. Journal of Biomedical Optics Vol.16(11) november 2011;Pubilshed:nov.10 2011,2011,16(11).
APA Li Hao,Jinglu,&guohuashiyudongzhang.(2011).Measurement of oxygen saturation in small retinal vessels with adaptive optics confocal scanning laser ophthalmoscope.Journal of Biomedical Optics Vol.16(11) november 2011;Pubilshed:nov.10 2011,16(11).
MLA Li Hao,et al."Measurement of oxygen saturation in small retinal vessels with adaptive optics confocal scanning laser ophthalmoscope".Journal of Biomedical Optics Vol.16(11) november 2011;Pubilshed:nov.10 2011 16.11(2011).
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