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Influence of Cr Adhesion Layer on Detection of Amyloid-Derived Diffusible Ligands Based on Localized Surface Plasmon Resonance
Zhu SL; Du CL; Fu YQ; et al.
Source PublicationPLASMONICS
Volume4Issue:2Pages:135-140
2009
Language英语
Indexed BySCI
Subtype期刊论文
AbstractA Cr adhesion layer inserted between Ag nanoparticles and a glass substrate, for the purpose of improving the adhesion of Ag nanoparticles to glass, was observed to cause an abnormal peak shift of extinction spectra in non-specific reactions. The undesired peak shift misleads molecule detection in non-specific reactions. To solve this issue, a practical technique using n-propyl-trimethoxysilane-based passivation for the detection of amyloid-derived diffusible ligands was investigated as a route to eliminate the abnormal peak shifting observed in the non-specific reactions. To evaluate this passivation technique, localized surface plasmon resonance immunoassay experiments were conducted. Experimental results derived with and without the passivation process were investigated as a basis for comparative analysis. Our experimental results demonstrate that this passivation technique effectively eliminates the observed peak shift originating from the Cr adhesion layer.
Document Type期刊论文
Identifierhttp://ir.ioe.ac.cn/handle/181551/4994
Collection微电子装备总体研究室(四室微光学)
Corresponding AuthorZhu SL
Affiliation中国科学院光电技术研究所
Recommended Citation
GB/T 7714
Zhu SL,Du CL,Fu YQ,et al. Influence of Cr Adhesion Layer on Detection of Amyloid-Derived Diffusible Ligands Based on Localized Surface Plasmon Resonance[J]. PLASMONICS,2009,4(2):135-140.
APA Zhu SL,Du CL,Fu YQ,&et al..(2009).Influence of Cr Adhesion Layer on Detection of Amyloid-Derived Diffusible Ligands Based on Localized Surface Plasmon Resonance.PLASMONICS,4(2),135-140.
MLA Zhu SL,et al."Influence of Cr Adhesion Layer on Detection of Amyloid-Derived Diffusible Ligands Based on Localized Surface Plasmon Resonance".PLASMONICS 4.2(2009):135-140.
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