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题名:
Influence of Cr Adhesion Layer on Detection of Amyloid-Derived Diffusible Ligands Based on Localized Surface Plasmon Resonance
作者: Zhu SL; Du CL; Fu YQ; et al.
刊名: PLASMONICS
出版日期: 2009
卷号: 4, 期号:2, 页码:135-140
通讯作者: Zhu SL
文章类型: 期刊论文
中文摘要: A Cr adhesion layer inserted between Ag nanoparticles and a glass substrate, for the purpose of improving the adhesion of Ag nanoparticles to glass, was observed to cause an abnormal peak shift of extinction spectra in non-specific reactions. The undesired peak shift misleads molecule detection in non-specific reactions. To solve this issue, a practical technique using n-propyl-trimethoxysilane-based passivation for the detection of amyloid-derived diffusible ligands was investigated as a route to eliminate the abnormal peak shifting observed in the non-specific reactions. To evaluate this passivation technique, localized surface plasmon resonance immunoassay experiments were conducted. Experimental results derived with and without the passivation process were investigated as a basis for comparative analysis. Our experimental results demonstrate that this passivation technique effectively eliminates the observed peak shift originating from the Cr adhesion layer.
收录类别: SCI
语种: 英语
内容类型: 期刊论文
URI标识: http://ir.ioe.ac.cn/handle/181551/4994
Appears in Collections:微电子装备总体研究室(四室微光学) _期刊论文

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作者单位: 中国科学院光电技术研究所

Recommended Citation:
Zhu SL,Du CL,Fu YQ,et al. Influence of Cr Adhesion Layer on Detection of Amyloid-Derived Diffusible Ligands Based on Localized Surface Plasmon Resonance[J]. PLASMONICS,2009,4(2):135-140.
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文件名: 2009-236.pdf
格式: Adobe PDF
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