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题名:
Measurement of oxygen saturation in small retinal vessels with adaptive optics confocal scanning laser ophthalmoscope
作者: Li, Hao; Lu, Jing; Shi, Guohua; Zhang, Yudong
刊名: JOURNAL OF BIOMEDICAL OPTICS
出版日期: 2011-11-01
卷号: 16, 期号:11
关键词: adaptive optics confocal scanning laser ophthalmoscope ; retinal oximetry ; retinal image registration ; spectrophotometry
文章类型: Article
英文摘要: We have used an adaptive optics confocal scanning laser ophthalmoscope to assess oxygen saturation in small retinal vessels. Images of the vessels with a diameter smaller than 50 mu m are recorded at oxygen sensitive and isosbestic wavelengths (680 and 796 nm, respectively). The vessel optical densities (ODs) are determined by a computer algorithm. Then, OD ratios (ODRs), which are inversely proportional to oxygen saturation, are calculated. The results show that arterial ODRs are significantly smaller than venous ODRs, indicating that oxygen saturation in the artery is higher than that in the vein. To the best of our knowledge, this is the first noninvasive measurement of oxygen saturation in small retinal vessels. (C) 2011 Society of Photo-Optical Instrumentation Engineers (SPIE). [DOI: 10.1117/1.3655354]
WOS标题词: Science & Technology ; Life Sciences & Biomedicine ; Physical Sciences
类目[WOS]: Biochemical Research Methods ; Optics ; Radiology, Nuclear Medicine & Medical Imaging
研究领域[WOS]: Biochemistry & Molecular Biology ; Optics ; Radiology, Nuclear Medicine & Medical Imaging
关键词[WOS]: OXIMETRY ; BLOOD
收录类别: SCI
语种: 英语
WOS记录号: WOS:000298546500002
Citation statistics:
内容类型: 期刊论文
URI标识: http://ir.ioe.ac.cn/handle/181551/3467
Appears in Collections:光电技术研究所被WoS收录文章_期刊论文

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作者单位: Chinese Acad Sci, Inst Opt & Elect, Grad Sch, Key Lab Adapt Opt, Chengdu 610209, Peoples R China

Recommended Citation:
Li, Hao,Lu, Jing,Shi, Guohua,et al. Measurement of oxygen saturation in small retinal vessels with adaptive optics confocal scanning laser ophthalmoscope[J]. JOURNAL OF BIOMEDICAL OPTICS,2011,16(11).
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