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题名:
Localized surface plasmon resonance-based hybrid Au-Ag nanoparticles for detection of Staphylococcus aureus enterotoxin B
作者: Zhu, Shaoli1,3; Du, ChunLei1; Fu, Yongqi2
刊名: OPTICAL MATERIALS
出版日期: 2009-09-01
卷号: 31, 期号:11, 页码:1608-1613
关键词: Hybrid Au-Ag nanoparticles ; Nano-biosensor ; LSPR ; Spectroscopy
文章类型: Article
英文摘要: A triangular hybrid Au-Ag nanoparticles array was proposed for the purpose of biosensing in this paper. Constructing the hybrid nanoparticles, an Au thin film is capped on the Ag nanoparticles which are attached on glass substrate. The hybrid nanoparticles array was designed by means of finite-difference and time-domain (FDTD) algorithm-based computational numerical calculation and optimization. Sensitivity of refractive index of the hybrid nanoparticles array was obtained by the computational calculation and experimental detection. Moreover, the hybrid nanoparticles array can prevent oxidation of the pure Ag nanoparticles from atmosphere environment because the Au protective layer was deposited on top of the Ag nanoparticles so as to isolate the Ag particles from the atmosphere. We presented a novel surface covalent link method between the localized surface plasmon resonance (LSPR) effect-based biosensors with hybrid nanoparticles array and the detected target molecules. The generated surface plasmon wave from the array carries the biological interaction message into the corresponding spectra. Staphylococcus aureus enterotoxin B (SEB), a small protein toxin was directly detected at nanogramme per milliliter level using the triangular hybrid Au-Ag nanoparticles. Hence one more option for the SEB detection is provided by this way. (C) 2009 Elsevier B.V. All rights reserved.
WOS标题词: Science & Technology ; Technology ; Physical Sciences
类目[WOS]: Materials Science, Multidisciplinary ; Optics
研究领域[WOS]: Materials Science ; Optics
关键词[WOS]: NANOSCALE OPTICAL BIOSENSOR ; BIOLOGICAL WARFARE AGENTS ; THREAT AGENTS ; MONOLAYER ; REAGENT ; PROBE ; ARRAY ; ASSAY
收录类别: SCI
语种: 英语
WOS记录号: WOS:000270613100012
Citation statistics:
内容类型: 期刊论文
URI标识: http://ir.ioe.ac.cn/handle/181551/3303
Appears in Collections:光电技术研究所被WoS收录文章_期刊论文

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作者单位: 1.Chinese Acad Sci, Inst Opt & Elect, Chengdu 610209, Peoples R China
2.Univ Elect Sci & Technol China, Sch Phys Elect, Chengdu 610054, Sichuan Prov, Peoples R China
3.Nanyang Technol Univ, Sch Elect & Elect Engn, Singapore 639798, Singapore

Recommended Citation:
Zhu, Shaoli,Du, ChunLei,Fu, Yongqi. Localized surface plasmon resonance-based hybrid Au-Ag nanoparticles for detection of Staphylococcus aureus enterotoxin B[J]. OPTICAL MATERIALS,2009,31(11):1608-1613.
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