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Influence of Cr Adhesion Layer on Detection of Amyloid-Derived Diffusible Ligands Based on Localized Surface Plasmon Resonance
Zhu, Shaoli1; Du, ChunLei1; Fu, Yongqi2; Deng, Qiling1; Shi, Lifang1
Source PublicationPLASMONICS
Volume4Issue:2Pages:135-140
2009-06-01
Language英语
Indexed BySCI
WOS IDWOS:000266390000007
SubtypeArticle
AbstractA Cr adhesion layer inserted between Ag nanoparticles and a glass substrate, for the purpose of improving the adhesion of Ag nanoparticles to glass, was observed to cause an abnormal peak shift of extinction spectra in non-specific reactions. The undesired peak shift misleads molecule detection in non-specific reactions. To solve this issue, a practical technique using n-propyl-trimethoxysilane-based passivation for the detection of amyloid-derived diffusible ligands was investigated as a route to eliminate the abnormal peak shifting observed in the non-specific reactions. To evaluate this passivation technique, localized surface plasmon resonance immunoassay experiments were conducted. Experimental results derived with and without the passivation process were investigated as a basis for comparative analysis. Our experimental results demonstrate that this passivation technique effectively eliminates the observed peak shift originating from the Cr adhesion layer.
KeywordLspr Addls Anti-addl Passivation Cr Adhesion Layer
WOS KeywordNANOSCALE OPTICAL BIOSENSOR ; SELF-ASSEMBLED MONOLAYERS ; ALZHEIMERS-DISEASE ; SILVER NANOPARTICLES ; SPECTROSCOPY ; A-BETA(1-42) ; NEUROTOXINS ; DEPENDENCE ; OLIGOMERS
WOS Research AreaChemistry ; Science & Technology - Other Topics ; Materials Science
WOS SubjectChemistry, Physical ; Nanoscience & Nanotechnology ; Materials Science, Multidisciplinary
Citation statistics
Cited Times:8[WOS]   [WOS Record]     [Related Records in WOS]
Document Type期刊论文
Identifierhttp://ir.ioe.ac.cn/handle/181551/3292
Collection光电技术研究所被WoS收录文章
Affiliation1.Chinese Acad Sci, Inst Opt & Elect, State Key Lab Opt Technol Microfabricat, Chengdu 610209, Peoples R China
2.Univ Elect Sci & Technol China, Sch Phys Elect, Chengdu 610054, Peoples R China
Recommended Citation
GB/T 7714
Zhu, Shaoli,Du, ChunLei,Fu, Yongqi,et al. Influence of Cr Adhesion Layer on Detection of Amyloid-Derived Diffusible Ligands Based on Localized Surface Plasmon Resonance[J]. PLASMONICS,2009,4(2):135-140.
APA Zhu, Shaoli,Du, ChunLei,Fu, Yongqi,Deng, Qiling,&Shi, Lifang.(2009).Influence of Cr Adhesion Layer on Detection of Amyloid-Derived Diffusible Ligands Based on Localized Surface Plasmon Resonance.PLASMONICS,4(2),135-140.
MLA Zhu, Shaoli,et al."Influence of Cr Adhesion Layer on Detection of Amyloid-Derived Diffusible Ligands Based on Localized Surface Plasmon Resonance".PLASMONICS 4.2(2009):135-140.
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