Chemical warfare agents (CWAs) are recognized as serious threats of terrorist acts against the civilian population. Minimizing the impact of these threats requires early detection of the presence of CWAs. Cavity ring-down spectroscopy (CRDS) is an exquisitely sensitive technique for the detection of trace gaseous species. In this letter, the CRDS technique is employed using a pulsed quantum cascade laser for the detection of dimethyl methylphosphonate (DMMP). A limit of DMMP detection of approximately 77 ppb is achieved. The best achievable sensitivity that corresponds to noise-equivalent absorption is approximately 2 x 10(-7) cm(-1).